CMC Project Leadership Partners with Biopharmaceutical Sciences LT members, and CMC PLs to ensure all projects have integrated CMC development plans, aligned with Disease Area Team's strategic program goals and objectives Leads a team of dedicated CMC Project Leaders, each accountable for ensuring the integrated development and on schedule execution of one or more CMC Pro

The Senior Quality Specialist is recognized as an expert internally in the principles and application of quality assurance and compliance. The Senior Quality Specialist coordinates GMP activities in support of clinical and commercial Drug Product manufacturing and disposition. This is an on site position on the 2nd shift. KEY DUTIES AND RESPONSIBILITIES Review batch data,

Responsible for all aspects of warehouse and materials management functions for the GMP/non GMP materials within the Boston and Cambridge warehouses (internal and external). Coach and lead a team of material handlers. Design organizational structure as needed. Act as Business Process Owner for materials management, collaborating with other Material Management leads within

Provide technical input into environmental/facility/process monitoring program deviations and contamination events to determine impact to batch disposition and design/implement effective corrective and preventative actions to prevent future disruptions. Strong collaboration in the resolution of manufacturing investigations related to aseptic control events Support the des

Develop engagement strategy and account plans to ensure success with target IDNs, GPOs and GPO aggregate accounts Engage with IDN, GPO and GPO aggregate account leadership, formulary decision makers, and population health stakeholders to ensure timely access and contracting, support product uptake, drive systemic change, and pursue creative partnerships, as appropriate Co

Develop engagement strategy and account plans to ensure success with target IDNs, GPOs and GPO aggregate accounts Engage with IDN, GPO and GPO aggregate account leadership, formulary decision makers, and population health stakeholders to ensure timely access and contracting, support product uptake, drive systemic change, and pursue creative partnerships, as appropriate Co

Develop engagement strategy and account plans to ensure success with target IDNs, GPOs and GPO aggregate accounts Engage with IDN, GPO and GPO aggregate account leadership, formulary decision makers, and population health stakeholders to ensure timely access and contracting, support product uptake, drive systemic change, and pursue creative partnerships, as appropriate Co

s and most effectively serve the needs of patients Develops and leverages high level relationships with patient advocacy groups at state and local levels to achieve Vertex goals, bring value to patients , and enhance the company's standing and reputation Serves as a liaison between the patient community and Vertex Collaborates with and facilitates advocacy coalitions for s

Lead the tactical execution of design planning, informing the development of scalable, effective distribution strategies to serve short and long term expectations while considering financial impacts and patient/customer experience Collaborate and drive alignment across key stakeholders on distribution and channel strategy development; apply subject matter expertise to max

The individual in this role will support the delivery of the patient and caregiver marketing strategy and tactical plan for our first genetic therapy for hemoglobinothapies (sickle cell disease and beta thalassemia), Casgevy. The Senior Marketing Manager will be responsible for overseeing development of brand and unbranded marketing tactics for the Sickle Cell disease ind

The Senior Director, Quality is responsible for the oversight of Product Quality Leads for all Vertex Small Molecule programs, development and commercial. As the group leader, the Sr. Director is responsible for supporting commercialization, filing/approval, launch, and post approval lifecycle management. This role will partner closely with Quality and business stakeholde

Lead and ensure successful development and implementation of the commercialization (midterm) and portfolio (long term) strategies including brand development, competitive strategy, go to market/launch, and lifecycle decisions for future launches. Execute in close partnership with the Regions, Market Access, Regulatory and Commercial Manufacturing. Deliver foundational ins

Vertex is seeking a talented individual to join the Engineering and Materials Science group in Boston, MA. The successful candidate will be a highly productive, results oriented individual, able to multi task and generate and implement original ideas that contribute to the successful development and scale up of drug substance processes, including crystallizations. Strong

The Sr. Director of Packaging and Labelling Operational Quality will advance compliance oversight for packaging and labelling validation, commercial supply, and product launches in North America and worldwide across the Small Molecule portfolio. The Sr. Director will have a broad role working with stakeholders across Manufacturing, Supply Chain and Regulatory. The role wi

The Analytical and Purification Principal Research Associate will lead the small molecule chiral purification platform within the Medicinal Chemistry group. The individual will propose and develop improvements in the purification workflow along with implementing new software and hardware technologies for high throughput separations. In addition, the successful applicant w